![]() While largely used to treat muscle spasms and pain, cyclobenzaprine has also been effective in treating the symptoms of fibromyalgia and tension headaches. It is still manufactured by Merck & Company under the brand name Flexeril and is distributed by McNeil Consumer & Specialty Pharmaceuticals. ![]() In 1977, it was approved by the US Food and Drug Administration (FDA) for treatment of muscle spasms. It is chemically related to tricyclic antidepressants, an early form of antidepressants invented in the 1950s.Īlthough cyclobenzaprine was found to have limited efficacy as an antidepressant, it proved very effective as a muscle relaxant. ![]()
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